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Justiniano maras
Moderators: Inga, Linas, Remigijus, Ibicus

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Posted 2014-02-03 02:26 (#95327)
Subject: Justiniano maras

Elite Veteran

Posts: 676
Trumpai supažindinu su straipsniu.

Veiksmas vyksta apie 500-600 metus.
Paul Deacon savo veikale rašo:
"Et haec quidem bad Italiam intra-off usque ad fines Alamannorum et gentium Baioariorum solis Romanis acciderunt."
Tuo maru sirgo tik romėnai ir Viduržemio jūros pakrantėje gyvenę žmonės. Tačiau Gotai ir Longobardai turėjo imunitetą.
"mentre Goti e Longobardi ne fossero immuni. "
To priežasti yra mutavęs genas genas CCR5-Δ32.
Kuris ir šiandien neleidžia įsisiūbuoti ŽIV epidemijai Lietuvoje (žirgo7 teksto interpretacija ).
Geno paplitimo žemėlapis duotas čia.
Galima įžiūrėti iš kur atėjo tie žmonės, labiausiai atsparūs Justiniano marui.

Vertimą į anglų pateikiu čia:

The Plague of Justinian in the History of Paul the Deacon
I believe Paul Deacon has been overlooked by historians, in fact, the text of the Historia to a more careful reading reveals many interesting details to better understand this early medieval period that marks the end of classical antiquity and the beginning of a new was for the history of Europe.

Plague of Justinian was named by the emperor Justinian (527-565), who at that time reigned over the Roman Empire of the East. This epidemic hit hard Constantinople between 541 and 542 in its most acute phase would have died more than 5,000 people a day, decimating the population of the capital by about 40% and reducing the population of the Eastern Mediterranean by 25%. It 'the same rate of mortality that occurred in northern Italy during the Gothic War.

Recent genetic studies done on the DNA of human remains from different historical periods have shown that the bacterium was the cause of the plague of Justinian belonged to a strain of Yersinia different from that of the black plague that afflicted Europe in the fourteenth century.

pestilence At Paul Deacon devotes one of the most impressive parts stylistically Historia Langobardorum , it is clear that he considered this event decisive for the decision of the Lombards invade Italy. The fact that Alboin decided to leave for Italy while he was over there in one of the worst plagues of the story is strange enough, but the Monaco Lombard explains why this epidemic is not frightened by the Lombards much.

Et haec quidem bad Italiam intra-off usque ad fines Alamannorum et gentium Baioariorum solis Romanis acciderunt .
These evils just hit the Romans in Italy to the borders with the Germans and Bavarians. Langobardorum History, Book II, Section 4
From the words of Paul the Deacon would seem that the plague had struck only the populations of Roman descent, while the Goths and Lombards they were immune. This is due to the fact that the peoples of northern Europe were carriers of a mutated gene (CCR5-Δ32) present in lymphocytes that was able to eradicate the bacteria that caused the plague dell'Yersinia, the populations of the Mediterranean had a different receptor protein ( CCR5 gene), which was instead very sensitive to this disease. As you can see from the chart below Scandinavia, homeland of the Goths and Lombards, is one of the places in the world with the increased presence of the gene CCR5-Δ32 in the population (15%), the mutation of this gene could have occurred in Scandinavia during the Mesolithic period (5000 years BC). It 's the same area that gave rise all'SNP R-U106 (Celtic-Germanic lineage) should be the Y-DNA haplogroup among other characteristics, that has a high incidence of mutation of the gene CCR5 delta 32.

This genetic mutation is very recent and may be due to an adaptation of the species to environmental conditions and climate change that occurred in the area since the last major glaciation or, hypothetically, interbreeding with Neanderthals (see post ).

According to recent studies, the CCR5-Δ32 gene would provide a greater immunological defense against other pandemics such as HIV, smallpox, and Ebola hemorrhagic fever and would play a role even in the absence of infection in the development of auto-immune diseases. E 'was also determined that the mutated gene was ineffective against the bubonic plague (Black Death) of the fourteenth century, which in fact resulted only in Britain a population reduction of 30-50%.

This terrible epidemic could be the reason why today majority of the populations of central and northern belongs to haplogroup R1b. The population of the Italian peninsula before the barbarian invasions had around 8 million people, after the epidemic at the end of the Gothic war this would have been reduced by 50% in a few years, but this reduction would only concern the populations of Latin origin. The absence of the CCR5-Δ32 mutation in the Etruscans could be the cause of their sudden disappearance in the third century BC as a result of a similar pandemic due to prolonged contact with the Celts in the Po Valley.

genetic mutation CCR5-Δ32 is also absent in 'Sub-Saharan Africa, in' the east and south-east Asia, the indigenous peoples of the Americas and Oceania. It 'very low in the Mediterranean basin and absent in the main islands.


Historia Langobardorum
Paul Deacon

Is the European spatial distribution of the HIV-1-resistant CCR5-Δ32 allele formed by a breakdown of the two pathocenosis to the historical Roman expansion?
Eric Faure, Manuela Royer-Carenzi
the Provence University, Marseille, France

The Geographic Spread of the CCR5 Δ32 HIV-Resistance Allele.
John Novembre, Alison P. Galvani, Montgomery Slatkin,
Department of Integrative Biology, University of California, Berkeley, California, USA

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